中国临床药理学杂志2016,Vol.32Issue(1):87-90,4.DOI:10.13699/j.cnki.1001-6821.2016.01.028
心肌纤维化与慢性充血性心力衰竭研究进展
Research advancement of myocardial fibrosis and chronic congestive heart failure
摘要
Abstract
Myocardial fibrosis ( MF ) is caused by various pathological factors which lead to a common pathology of heart disease till apposite phase time , and it is also main cause of ventricular remodeling .Research of modern medicine demonstrate that there is close relationship between myocardial fibrosis and various cardiovascular disease , such as hyperten-sive heart disease , ischemic cardiomyopathy , hypertrophic cardiomyopa-thy, dilated cardiomyopathy, viralmyocarditis, diabetic cardiomyopathy and so on.This paper will review interrelated research advancement of myocardial fibrosis and chronic congestive heart failure from renin -angiotensin-aldosterone system(RAAS), MF regulatory cytokines, in-flammatory cytokines and vascular endothelial growth factor .关键词
心肌纤维化/慢性充血性心力衰竭/肾素—血管紧张素—醛固酮系统/心肌纤维化调控细胞因子Key words
myocardial fibrosis/chronic congestive heart failure/renin-angiotensin -aldosterone system/myocardial fibrosis regulatory cytokines分类
医药卫生引用本文复制引用
施洋,李澜,邢晓雪,樊官伟..心肌纤维化与慢性充血性心力衰竭研究进展[J].中国临床药理学杂志,2016,32(1):87-90,4.基金项目
国家重点基础研究发展计划(973计划)基金资助项目(2012CB518404) (973计划)
国家自然科学基金资助项目(81273891) (81273891)
教育部"创新团队发展计划"基金资助项目(IRT1276) (IRT1276)