中国实用外科杂志2016，Vol.36Issue(1)：119-121,3.DOI:10.7504/CJPS.ISSN1005-2208.2016.01.31
原发性甲状旁腺功能亢进术后低钙血症相关因素分析
Risk factors of hypocalcemia after parathyroidectomy for primary hyperparathyroidism
胡亚 1廖泉 1曹少博 1高翔 1王梦一 1赵玉沛1
作者信息
- 1. 中国医学科学院 北京协和医学院北京协和医院基本外科,北京100730
- 折叠
摘要
Abstract
Objective Hypocalcemia is a common condition after parathyroidectomy in the patients with primary hyperparathyroidism. The risk factors of post-operative hypocalcemia was sought to identify in this study. Methods A database about parathyroid lesions in Peking Union Medical College Hospital was searched for the patients with primary hyperparathyroidism who underwent successful parathyroidectomy between January 2009 and March 2015. Patients with malignant or familial parathyroid lesions were excluded. The possible risk factors were investigated including gender, age, preoperative calcium, phosphate, intact parathyroid hormone (iPTH) and alkaline phosphatase (ALP) levels. Results Of the 641 patients included in this study, 118 (18.4%) and 210 (32.8%) patients were diagnosed with postoperative hypocalcemia with biochemical criteria and symptomatic criteria, respectively. By applying multivariate stepwise logistic regression analysis, age, pre-operative serum phosphate and ALP level had predictive value for development of early hypocalcemia with symptomatic criteria. And the pre-operative serum iPTH level was the risk factors for the hyopcalcemia with biochemical criteria. Conclusions The age, pre-operative serum phosphate, ALP and iPTH levels were related with postoperative hypocalcemia. Patients with one or more of these factors should be monitored for possible complications with hypocalcemia.关键词
原发性甲状旁腺功能亢进/甲状旁腺切除术/低钙血症Key words
primary hyperparathyroidism/parathyroidectomy/hypocalcemia分类
医药卫生引用本文复制引用
胡亚,廖泉,曹少博,高翔,王梦一,赵玉沛..原发性甲状旁腺功能亢进术后低钙血症相关因素分析[J].中国实用外科杂志,2016,36(1):119-121,3.
