中国药理学通报Issue(12)：1715-1718,4.DOI:10.3969/j.issn.1001-1978.2015.12.017
葎草中黄酮类成分的分离鉴定及对小鼠肺水清除率的影响
Separation and identification of flavonoid constituent in Humulus Scandens and their effects on alveolar fluid clearance in mice
摘要
Abstract
Aims To extract,separate and identify the flavonoid constituents in Humulus Scandens and to ex-plore the relationship of monomers and alveolar fluid clearance (AFC)in mice in vivo.Methods Humulus scandens were extracted with alcohol and then isolated by the technology of Column and the structures were i-dentified by spectrometry.In vivo AFC was measured using bovine serum albumin protein assays affected by luteolin-7-O-β-D-glucoside (LGL ) and cosmsiin (AGL).Results The main constituents of flavanones <br> in Humulus scandens were LGL and AGL.Both of them could improve the AFC.Conclusion The AFCs of LGL and AGL,compared to the blank control group, increased which explains the effect of flavonoid constit-uents on removing edema and promoting water absorp-tion.关键词
葎草/化学成分/木犀草苷/大波斯菊苷/肺水清除率/肺水肿Key words
Humulus Scandens/chemical constituent/luteolin-7-O-β-D-glucoside/cosmsiin/alveolar fluid clearance (AFC)/pulmonary edema分类
医药卫生引用本文复制引用
陈再兴,王星,祝妍,王琳,王岩,聂宏光,孟繁浩..葎草中黄酮类成分的分离鉴定及对小鼠肺水清除率的影响[J].中国药理学通报,2015,(12):1715-1718,4.基金项目
辽宁省自然科学基金资助项目 （）
