摘要
Abstract
76 premature babies stayed in NICU of Taian City Central Hospital from January, 2012 to December, 2012 whose gestational age is from 31 week to 35 week. The babies were scanned with MRI, DTI and MRS. According to the statistics of Brain White Matter Damage Based on MRI those babies are divided into case group and control group which has 38 babies respectively. 38 full-term infants, who don’t have history of perinatal asphyxia, whose MRI is normal, are taken as control group. The ADC value and FA value in different ROIs and different metabolite peak ratios in two groups are tested with DTI and MRS respectively.Results: 1.With the growth of gestational age the ADC value decreases while the FA value increase gradually. 2.With the deterioration of white matter damage the values of Cho, Lac, Cho/Cr, Cho/NAA rise while the values of NAA, NAA/Cho, NAA/Cr fall.Conclusion: Cerebral white matter damage can severely influence the changes of brain inner water molecular diffusion and anisotropy and metabolin. By uniting the DTI and MRS these two technologies together, people can diagnose cerebral white matter damage and white matter damage in the early period.关键词
早产儿/脑白质损伤/磁共振弥散张量成像/磁共振波谱成像Key words
Prematurity/Cerebral white matter damage/Diffusion tensor imaging/Magnetic resonance spectroscopy分类
医药卫生
