摘要
Abstract
Objective To investigate the efficacy of metoprolol in Treating autonomic nervous system imbalance of patients with acute ST segment elevation myocardial infarction. Methods A 101 cases of patients with acute ST segment elevation myocardial infarction from May 2013 to May 2014 were selected and randomly divided into the treatment group of 50 cases and the control group with 50 cases. After admission,all patients were treated with anticoagulation,lipid-lowering and anti-platelet drugs,on this basis,the control group was given nifedipine(Ⅱ)and the treatment group metoprolol succinate. Results After treatment,HRV time domain and the fre-quency domain indicators of the treatment groups were obviously better than the control group ( P < 0. 05,P < 0. 01);the cardiac function of the two groups showed different degrees of improvement ( P < 0. 05);the reoccurrence rate of myocardial infarction in the treatment group was 6. 00%,which was obviously lower than 11. 10% in the control group ( P < 0. 05);after treatment,the cardiac markers,blood lipid parameters(except high density lipoprotein cholesterol),hs-CRP in the two groups had statistically significant dif-ferences ( P < 0. 05). Conclusions Metoprolol can improve HRV in the acute ST-segment elevation myocardial infarction,and has good efficacy in the restoration of the autonomic nervous imbalance and heart function,reducing the frequency of reoccurrence,improving blood lipid and hs-CRP.关键词
急性ST段抬高型心肌梗死/美托洛尔/心率变异性Key words
acute ST-segment elevation myocardial/metoprolol/heart rate variability分类
医药卫生
