化工进展Issue(1)：243-247,5.DOI:10.16085/j.issn.1000-6613.2016.01.033
1,3,2-二唑噻吩-2,2-二氧化物的合成工艺优化
Optimization of the synthesis of 1,3,2-dioxathiolane 2,2-dioxide
摘要
Abstract
1,3,2-dioxathiolane -2,2-dioxide was synthesized by ethylene glycol and thionyl chloride, with the heterogeneous catalyst of ruthenium(III) chloride and various oxidants. The product was characterized by1H NMR and IR spectra. The effects of different oxidants,molar ratio of raw materials,reaction temperature,reaction time,and the amount of oxidants and catalyst on the yield of target product were investigated. The optimal reaction conditions were determined as:n(thionyl chloride)∶n(ethylene glycol)=1.2∶1,m(sodium periodate)∶m(ethylene glycol)=3∶1,m(catalyst)∶m(ethylene glycol)=0.002∶1 and the reaction were carried out at 40℃ for 60 min using sodium periodate as oxidant. The yield of the product could reach 81.25% under the above optimal reaction conditions. The new process has the advantages of fewer by-products,lower toxicity and higher yield and therefore are more valuable in practical application.关键词
乙二醇/1,3,2-二/唑噻吩-2,2-二氧化物/氧化/合成/优化Key words
ethylene glycol/1,3,2-dioxathiolane-2,2-dioxide/oxidation/synthesis/optimization分类
化学化工引用本文复制引用
王培红,张楠,周宝强,高瑞昶..1,3,2-二唑噻吩-2,2-二氧化物的合成工艺优化[J].化工进展,2016,(1):243-247,5.
