湖南大学学报（自然科学版）Issue(12)：53-58,6.
生物活性多甲氧基黄酮糖苷的合成及其结构表征
Synthesis and Structure Characterization of Bioactive Polymethoxyflavonoids Glycosides
摘要
Abstract
Two most abundant sources with the highest anticancer activity of natural polymethoxyfla-vonoids were oxidated by dimethyldioxirane (DMDO )to polymethoxy flavonoids 9 and 10 respectively.9 or 10 were condensed withα-acetylglucosyl bromide,α-acetylgalactosyl bromide or α-acetylrhamnosyl bro-mide in dilute NaOH (aq)/CHCl3 system through phase transfer catalytic glycosation reaction,and fol-lowed by deacetylation,four new polymethoxyflavonoids glycosides 1~4 were synthesized.The structures of all the synthesized compounds were characterized by 1 HNMR,13 CNMR and MS spectra.This synthetic method has the advantages of easy availability of starting materials,simple operation.关键词
合成/多甲氧基黄酮/糖苷化反应/结构表征Key words
synthesis/polymethoxyflavonoids/glycosation reaction/structure characterization分类
化学化工引用本文复制引用
汪秋安,王盛淳,李悦,单杨..生物活性多甲氧基黄酮糖苷的合成及其结构表征[J].湖南大学学报（自然科学版）,2015,(12):53-58,6.基金项目
国家自然科学基金资助项目（J1210040），National Natural Science Foundation of China（J1210040）；“十二五”农村领域国家科技计划项目 （）
