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美沙拉嗪治疗老年溃疡性结肠炎的临床效果观察

樊震宇 贾华锋 田广

检验医学与临床Issue(1):75-76,2.
检验医学与临床Issue(1):75-76,2.DOI:10.3969/j.issn.1672-9455.2016.01.031

美沙拉嗪治疗老年溃疡性结肠炎的临床效果观察

Observation on clinical effect of mesalazine in treating elderly ulcerative colitis

樊震宇 1贾华锋 1田广1

作者信息

  • 1. 江苏省如皋博爱医院消化内科,江苏如皋 226500
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摘要

Abstract

Objective To investigate the clinical effect of mesalazine in treating elderly ulcerative colitis(UC). Methods 68 cases of elderly UC in our hospital were selected and randomly divided into the observation group (u-sing mesalazine)and the control group (using sulfasalazine),34 cases in each group.The clinical symptoms,colono-scopic results,defecate frequency and the change of liver and kidney function were compared between the two groups. Results The total effective rate of the observation group was 94.1%,which of the control group was 79.4%,the treatment effect of the observation group was better than that of the control group,the difference was statistically significant (P <0.05).The occurrence rate of adverse reactions was 8.8% in the observation group and 29.4% in the control group,the difference was statistically significant (P <0.05).Conclusion Mesalazine has the remarkable effect with lower adverse drug reaction and higher security in the treatment of elderly UC.

关键词

美沙拉嗪/老年溃疡结肠炎/柳氮磺吡啶/临床效果

Key words

mesalazine/elderly ulcerative colitis/sulfasalazine/clinical treatment

引用本文复制引用

樊震宇,贾华锋,田广..美沙拉嗪治疗老年溃疡性结肠炎的临床效果观察[J].检验医学与临床,2016,(1):75-76,2.

检验医学与临床

1672-9455

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