护理学报Issue(24)：1-6,6.DOI:10.16460/j.issn1008-9969.2015.24.001
认知行为疗法对乳腺癌患者抑郁和生活质量的影响系统评价和Meta分析
Influence of Cognitive Behavioral Therapy on Depression and Quality of Life in Patients with Breast Cancer:A Systematic Review and Meta-analysis
摘要
Abstract
Objective To evaluate the effect of cognitive behavioral therapy on improving depression and quality of life on patients with breast cancer. Methods We searched PubMed,CBM,Wanfang Data,VIP and CNKI to collect randomized controlled trials (RCTs) on improving depression and the quality of life in patients with breast cancer from the establishment of these databases to Dec. 30th, 2014. Two reviewers screened literature independently according to the inclusion and exclusion criteria, extracted data, and assessed methodol-ogical quality. Meta-analysis was conducted by RevMan 5.2. Results Ten RCTs involving 894 patients were idenified and the quality level of the literatures was grade B. The funnel plot taking despression as outcome indicator showed asymmetry, indicating that there was publication bias. Meta-analysis indicated that cognitive behavioral therapy significantly improved depression [MD=-1.22, 95%CI(-1.44,-1.00), P<0.00001], [MD=-5.83,95%CI(-8.10,-3.56), P<0.00001]; [SMD=1.42,95%CI(1.09, 1.75), P<0.00001],[SMD=0.57, 95%CI(0.23,0.92),P=0.001] and descriptive result showed that cognitive behavioral therapy had the effect on improving the quality of life of patients with breast cancer on the overall. Conclusion Cognitive behavioral therapy can reduce depression and improve the quality of life of patients with breast cancer.关键词
乳腺癌/认知行为疗法/抑郁/生活质量/系统评价Key words
breast cancer/cognitive behavioral therapy/depression/quality of life/systematic review/meta-analysis分类
医药卫生引用本文复制引用
王秋萍,章新琼,朱宇,吕晓晴,王晓灿,罗群,王维利..认知行为疗法对乳腺癌患者抑郁和生活质量的影响系统评价和Meta分析[J].护理学报,2015,(24):1-6,6.基金项目
安徽省第二批科技计划项目资助（1303063025）；安徽高校省级自然科学基金项目 （）
