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腺苷A2A受体基因敲除小鼠繁殖能力分析

王一龙 管敏强 李安乐 李渊 安建宏

畜牧与饲料科学Issue(12):17-18,2.
畜牧与饲料科学Issue(12):17-18,2.

腺苷A2A受体基因敲除小鼠繁殖能力分析

Analysis on Reproductive Capacity of Adenosine A2A Receptor Gene Knockout Mice

王一龙 1管敏强 1李安乐 1李渊 2安建宏2

作者信息

  • 1. 温州医科大学实验动物中心,浙江 温州 325035
  • 2. 温州医科大学眼视光学院,浙江 温州 325035
  • 折叠

摘要

Abstract

In order to improve the reproductive capacity of adenosine A2A receptor gene knockout mice and strengthen their breed conservation working, the reproductive capacity of adenosine A2A receptor gene knockout mice was analyzed based on their reproductive record. The results showed that while no significant differences of average litter size were observed in the generations of Fback cros , F1 and F2 (P>0.05), the average litter size of Fback cros , F1 and F2 were all significantly higher than that of F3 (P<0.01). It was indicated that the reproductive capacity of adenosine A2A receptor gene knockout mice decreased with the increase of generations, but their reproductive capacity can be improved by back cross.

关键词

小鼠/腺苷A2A/基因敲除/繁殖/产仔数

Key words

mice/adenosine A2A/gene knockout/reproductivity/litter size

分类

生物科学

引用本文复制引用

王一龙,管敏强,李安乐,李渊,安建宏..腺苷A2A受体基因敲除小鼠繁殖能力分析[J].畜牧与饲料科学,2015,(12):17-18,2.

基金项目

浙江省科技计划项目(实验动物科技计划项目,2012C37100)。 ()

畜牧与饲料科学

1672-5190

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