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添加羊乳粉对乙型肝炎肝硬化患者营养状态及肝脏合成功能的影响

朱慧 郭红英 黄大青 张宇一 张正国 邹颖 王介非 钱志平

实用肝脏病杂志Issue(1):64-67,4.
实用肝脏病杂志Issue(1):64-67,4.DOI:10.3969/j.issn.1672-5069.2016.01.016

添加羊乳粉对乙型肝炎肝硬化患者营养状态及肝脏合成功能的影响

Improvement of goat m ilk powder diet on nutrition states and synthetic function of liver in patients with hepatitis B-induced cirrhosis

朱慧 1郭红英 1黄大青 1张宇一 1张正国 1邹颖 1王介非 1钱志平1

作者信息

  • 1. 201508上海市 复旦大学附属公共卫生临床中心重症肝炎/ICU科
  • 折叠

摘要

Abstract

Objective To observe the effects of goat milk powder diet on nutrition condition and synthetic function of liver in patients with hepatitis B-induced liver cirrhosis. Methods Eighty patients with hepatitis B-related liver cirrhosis were enrolled in this study,and 40 cases were treated with goat milk powder in treatment group and 40 cases were treated with regular dieteric were treatment in control group. Evaluation of nutrition condition and liver function tests were conducted for 12 weeks in both groups. Analyses were carried out by using t test. Results At 4 week and 8 week observation,there was no significant difference of nutrition indicators and liver synthetic funtion,including body mass index,arm muscle circumference,serum albumin,pre-albumim, transferrin and cholinesterase levels between the two groups;the body mass index [(23.36 ±1.26) kg/m2 vs. (22.30±1.80) kg/m2,t=3.021,P<0.05],arm muscle circumstance[(27.89±2.85) cm vs.(26.16±3.04) cm,t=2.766,P<0.05],albulmin [(34.93±1.63) g/L vs.(32.04±1.80) g/L,t=7.597,P<0.05],pre-albulmin [(91.97±21.14) mg/L vs. (76.92 ±15.94)mg/L,t=3.415,P<0.05],transferrin [(1.69 ±0.35) mg/L vs.(1.50 ±0.34) mg/L,t=2.315,P<0.05] and cholinesterase [(2785 ±516)U/L vs.(2546 ±487) U/L,t=2.105,P<0.05] in the treatment group at week 12 were significantly increased as compared to those in the control group,while the serum levels of total bilirubin,blood ammonia, plasma triglyceride and blood sugar showed no significant differences between the two groups. Conclusions Dietary intervention with goat milk powder can improve nutrition condition and liver synthetic function in patients with hepatitis B-induced liver cirrhosis.

关键词

肝硬化/乙型肝炎/羊乳粉/营养

Key words

Liver cirrhosis/Hepatitis B/Goat milk powder/Nutrition

引用本文复制引用

朱慧,郭红英,黄大青,张宇一,张正国,邹颖,王介非,钱志平..添加羊乳粉对乙型肝炎肝硬化患者营养状态及肝脏合成功能的影响[J].实用肝脏病杂志,2016,(1):64-67,4.

实用肝脏病杂志

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1672-5069

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