中国临床药理学杂志Issue(24)：2451-2453,3.DOI:10.13699/j.cnki.1001-6821.2015.24.025
万古霉素在老年患者中的临床用药调查分析
Investigation of vancomycin used in geriatric patients
盛晓燕 1高菲菲 2马陵悦 1陈超阳 1周颖 1崔一民1
作者信息
- 1. 北京大学第一医院药剂科，北京 100034
- 2. 中国药科大学 药学院 临床药学系，南京211198
- 折叠
摘要
Abstract
Objective This study is to investigate the use of vancomycin in geriatric patients and promote the safe and rational usage of vancomy-cin.Methods By retrospective analysis, data were extracted from medical records of 180 geriatric patients who intravenously used vancomy-cin in 2014 in terms of etiology check, diseases, therapeutic drug moni-toring, medication duration, therapeutic efficacy, etc. Results The treatment of vancomycin in 58.88%geriatric patients was based on expe-rience and 75.55% geriatric patients use vancomycin to treat infection instead of pretending infection and the effective rate was 38.89%.The biggest reason to use vancomycin was pulmonary infection ( 54.37%) , 87.78% of the patients completed etiology check and drug sensitive test, and staphylococcal infection accounts for 16.29%of the positive results, 29.44% of the patients completed therapeutic drug monitoring. Conclusion Most of the usage is rational.The time of treatment is still to be discussed.The treatment is mainly based on the experience.Thera-peutic drug monitoring ( TDM ) is under specification.Clinical pharma-cists should try to make the monitor time in clinic and the application of vancomycin in the geriatric patients more reasonable .关键词
万古霉素/治疗药物监测/老年患者/合理用药Key words
vancomycin/therapeutic drug monitoring/geriatric patients/drug rational use分类
医药卫生引用本文复制引用
盛晓燕,高菲菲,马陵悦,陈超阳,周颖,崔一民..万古霉素在老年患者中的临床用药调查分析[J].中国临床药理学杂志,2015,(24):2451-2453,3.
