中国临床药理学杂志Issue(24)：2459-2461,3.DOI:10.13699/j.cnki.1001-6821.2015.24.028
利奈唑胺不良反应的文献计量分析
Linezolid analysis of research papers in the subject of adverse drug reaction
摘要
Abstract
Objective To comprehensively the linezolid clinical applica-tion of the occurrence of adverse drug reaction, distribution, severity, and effective prevention and control measures, more reasonable, safe for clinical use of linezolid provides the reference basis.Methods English search PubMed, EMbase, and Web of Science database, Chinese search CNKI and Wanfang about the document of the linezolid adverse drug reaction, the deadline in June 2014, use Endnote X7 sorting.Distribution and the literature involves the basic diseases and the treatment measures, summarizes the major adverse drug reaction of the linezolid type, site, severity, clinical manifestations and prevention measures were ana-lysed.Results Participants included 233 references.For the first time linezolid adverse drug reaction of literatures published in 2000, 49 num-ber reaches its peak in 2012.The paper number among the five countries, China (37), the United States (25), Britain (14), Spain (6), New Zealand (5).Literature cited frequency highest was 94.This paper in-volves the injection using linezolid cause severe nervous system toxicity and digestive system adverse drug reaction, aroused people′s concern. Conclusion By reducing the course of medication, dose, or strict tes-ting patients′blood picture during the medication, prevent adverse drug reaction occur.关键词
利奈唑胺/不良反应/文献计量分析Key words
linezolid/adverse drug reaction/literature analysis分类
医药卫生引用本文复制引用
白艳,王羽凝,李其,王天琳,孙艳,王瑾,王睿..利奈唑胺不良反应的文献计量分析[J].中国临床药理学杂志,2015,(24):2459-2461,3.基金项目
十二五国家重大科技专项基金资助项目（2012ZX09303004－002）；解放军总医院临床科研扶持基金 （）
