中国比较医学杂志Issue(12)：75-80,6.DOI:10.3969.j.issn.1671-7856.2015.12.015
IL－37对炎症相关性疾病的抑制作用
Inhibitory effect of IL-37 on inflammation-related diseases
摘要
Abstract
Inteleukin-37 is a member of IL-1 family and originally named as IL-1F7.It has five different subtypes (IL-37a-e).It has been reported that IL-37 suppresses pro-inflammatory cytokines production of a variety of immune cells, and further regulate innate immune response. In addition, IL-37 has protective effects on colitis, arthritis, pancreatitis and other inflammatory diseases that induced by exogenous stimuli. In a word, IL-37 is a novel anti-inflammatory cytokine and plays an important role in a variety of inflammation-related diseases.关键词
IL-37/炎症抑制因子/炎性疾病Key words
IL-37/Anti-inflammatory cytokine/Inflammation-related diseases分类
医药卫生引用本文复制引用
李梦媛,杨星九,徐大模,高苒..IL－37对炎症相关性疾病的抑制作用[J].中国比较医学杂志,2015,(12):75-80,6.基金项目
协和青年基金资助，中央高校基本科研业务费专项资金资助（33320140192），中国医学科学院医学实验动物研究所基本科研业务费专项资助（ DWS201301）。 （）
