中国医科大学学报Issue(12)：1057-1060,4.
利用频域光学相干断层扫描测量青光眼视盘旁萎缩区
Application of Spectral-domain Optical Coherence Tomography for Measuring Peripapillary Atrophy in Glaucoma
摘要
Abstract
Objective to measure peripapillary atrophy(PPA)in glaucoma with high-resolution spectral domain-optical coherence tomography (SD-OCt)and conventional color fundus photograph,and compare the consistency of the results between the two imaging methods. Methods A to-tal of 30 patients(54 eyes)with glaucoma from Department of Opthalmology,the First Hospital,China Medical University were prospectively includ-ed for the study. SD-OCt images and color fundus photographs taken through the region of PPA were qualitatively analyzed. the average width of β-PPA area in 6 reference lines centered optic nerve were measured using SD-OCt and color fundus photograph. Correlation and agreement between the two measuring methods were analyzed. Results the average width of β-PPA was 229.89±99.82 μm using color fundus photographs and 224.14±97.10 μm using SD-OCt,respectively. there was no significant difference(P = 0.280). the correlation coefficient was 0.825 between re-sults measured by SD-OCt and color fundus photographs for β-PPA area(P < 0.001),and agreement between the two methods was good(ICC=0.923,95% CI 0.870-0.954). Conclusion the correlation and consistency is good between SD-OCt and conventional color fundus photograph measuring β-PPA area. β-PPA area can be estimated with SD-OCt.关键词
青光眼/视盘旁萎缩区/频域光学相干断层扫描Key words
glaucoma/peripapillary atrophy/spectral domain-optical coherence tomography分类
医药卫生引用本文复制引用
马小力,刘贤洁,陈禹橦,李丹丹,张宏伟,华瑞..利用频域光学相干断层扫描测量青光眼视盘旁萎缩区[J].中国医科大学学报,2015,(12):1057-1060,4.基金项目
国家自然科学基金（81200656）；辽宁省博士启动基金 （）
