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替米沙坦与苯磺酸氨氯地平联用对高血压合并2型糖尿病患者血脂及血糖的影响

姜秀凤 姜德华

中国药物经济学Issue(1):56-59,4.
中国药物经济学Issue(1):56-59,4.DOI:10.12010/j.issn.1673-5846.2016.01.027

替米沙坦与苯磺酸氨氯地平联用对高血压合并2型糖尿病患者血脂及血糖的影响

Effects of using Telmisartan and Amlodipine Besylate on the Blood lipid and Blood Glucose of Patients with Type 2 Diabetes Mellitus and Hypertension

姜秀凤 1姜德华1

作者信息

  • 1. 辽宁省普兰店市中心医院药剂科,辽宁大连 116200
  • 折叠

摘要

Abstract

Objective To compare the effect of using Telmisartan combined with Amlodipine Besylate and using single Amlodipine Besylate on the blood lipid and blood glucose of Hypertension Type 2 diabetes melitus patients. MethodsFrom April 2013 to April 2014,112 patients with hypertension and diabetes in Pulandian City Center Hospital of Liaoning province were selected as the research object,and according to the random number table method,the patients were divided into observation group and control group,56 cases in each.The observation group was treated with Telmisartan(40~80mg),Amlodipine Besylate(2.5~5 mg),the control group was given Amlodipine Besylate (2.5~5mg),1 times/d,the morning meal served with corresponding drugs,continuous observation for 24 weeks,compared the changes of blood pressure,blood lipid,blood glucose and the body mass index of the two groups before and after treatment,and record adverse reactions.Results After 24 weeks treatment,the observation group triglyceride(TG), fasting blood glucose(FBG) compared with those before treatment were significantly reduced(P<0.05), compared with the control group after treatment was statisticaly significant(P<0.05),the observation group’s low density lipoprotein cholesterol(LDL-C)decreased significantly compared with before treatment(P<0.05),no statistical significance comp- ared with the control group after treatment(P>0.05) difference.Conclusion The combination of Telmisartan and Amlodipine Besylate can not only control blood pressure for patients with type 2 diabetes melitus and hypertension, but also significantly improve the patient's blood lipids,blood glucose.

关键词

替米沙坦/苯磺酸氨氯地平/高血压/糖尿病/血脂/血糖

Key words

Telmisartan/Amlodipine Besylate/Hypertension/Diabetes melitus/Blood lipid/Blood glucose

分类

医药卫生

引用本文复制引用

姜秀凤,姜德华..替米沙坦与苯磺酸氨氯地平联用对高血压合并2型糖尿病患者血脂及血糖的影响[J].中国药物经济学,2016,(1):56-59,4.

中国药物经济学

1673-5846

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