中国医药科学Issue(21)：54-56,3.
离子色谱法测定可溶性焦磷酸铁中柠檬酸、焦磷酸的含量
Determination of citrate and pyrophosphoric acid in ferric pyrophosphate by ion chromatography
钟春华 1陈刚胜 1李孝壁 1姜涛 1胡春勇1
作者信息
- 1. 江苏豪森药业股份有限公司，江苏连云港 222069
- 折叠
摘要
Abstract
Objective To establish a method the determination of citrate and Pyrophosphoric acid in Ferric Pyrophosphate by ion chromatography.MethodsThe determination was carried out on a Dionex IonPac AS11 (4mm×250mm) column with 10mmol/L Sodium hydroxide solution as eluent by electrical conductivity detector. The flow rate was 1.0mL/min,The column temperature was 30℃,and temperature of conductivity detection pool was 35℃. Results The citrate was a good linearity over the range of 0.05-3.06μg/mL with a the correlation coefficient r higher than 0.9990(n=6).The RSD for repeatition was 0.39%(n=6).The Pyrophosphoric acid was a good linearity over the range of 0.06-4.48μg/mL with a the correlation coefficient r higher than 0.9990(n=6),the RSD for repeatition was 0.32%(n=6). Conclusion The method is environmental friendly and has high sensitivity,good selectivity,and can meet the requirement of the determination of citrate and Pyrophosphoric acid in Ferric Pyrophosphate.关键词
离子色谱/可溶性焦磷酸铁/柠檬酸/焦磷酸Key words
Ion chrmatography/Ferric Pyrophosphate/Citrate/Pyrophosphoric acid分类
医药卫生引用本文复制引用
钟春华,陈刚胜,李孝壁,姜涛,胡春勇..离子色谱法测定可溶性焦磷酸铁中柠檬酸、焦磷酸的含量[J].中国医药科学,2015,(21):54-56,3.
