中华灾害救援医学Issue(1)：9-11,3.DOI:10.13919/j.issn.2095-6274.2016.01.003
急诊患者血清N末端脑钠肽前体水平与病情评估及预后的相关性研究
Correlation study between serum N-terminal pro-brain natriuretic peptide levels and condition assessment and prognosis of emergency patients
王宗科 1李桂花1
作者信息
- 1. 832000，新疆维吾尔自治区石河子大学医学院第一附属医院急诊内科
- 折叠
摘要
Abstract
Objective To explore relationship between serum N-terminal pro-brain natriuretic peptide (NT-proBNP) and condition assessment and prognosis of patients in department of emergency. Methods 208 patients from department of emergency were recruited as research objects. Serum level of NT-proBNP was measured and patients were grouped according to acute physiology and chronic health evaluation system Ⅱ (APACHE Ⅱ ) score within the first 24 h after admission. The relationship between serum NT-proBNP and APACHE Ⅱ score, and their relationships with fatality rate and left ventricular ejection fraction (LVEF) of emergency patients were analyzed. Results Serum NT-proBNP levels showed statistically significant differences among different APACHEⅡscore groups (χ2=68.07, P<0.01). The level of serum NT-proBNP was positively correlated with APACHE Ⅱ score (rs=0.60,P < 0.01). Patients were followed up for 3 months, NT-proBNP level (Z=6.50,P < 0.01) and APACHE Ⅱ score (t’=-16.65,P < 0.01) in death group were significantly higher than those in survival group (P < 0.05). NT-proBNP level in group LVEF ≤ 50% was higher than that in group LVEF > 50%(Z=7.72,P < 0.01), but the difference of APACHE Ⅱ score between two groups had no statistical significance. Conclusions Serum NT-proBNP level is positively correlated with patient’s condition and fatality rate, and may be applied to evaluate condition and prognosis of emergency patients.关键词
N 末端脑钠肽前体/急诊患者/病情评估/预后Key words
N-terminal pro-brain natriuretic peptide/emergency patients/condition assessment/prognosis分类
医药卫生引用本文复制引用
王宗科,李桂花..急诊患者血清N末端脑钠肽前体水平与病情评估及预后的相关性研究[J].中华灾害救援医学,2016,(1):9-11,3.
