摘要
Abstract
Objective To investigate the efficacy of polyene phosphatidyl choline combined with adenosine methionine effects on liver fibrosis of patients with alcoholic liver cirrhosis. Methods 72 cases of patients with alcoholic liver cirrhosis from January 2014 to April 2015 were selected and randomly divided into observation group and control group, 36 cases in each group. The control group was given polyene phosphatidyl choline, and the treatment group was given polyene phosphatidyl choline and adenosine methionine. Results After treatment, the total effective rate of the observation group was 83. 33%, which was significantly higher than 69. 44% of the control group ( P < 0. 05 );the ALT, AST, ALP and TBIL expression level of the two groups decreased compared with before treatment, and the observation group decrease more statistically ( P < 0. 05 ); the HA, P-M-P, LN and C-Ⅳ expression levels of the two groups de-creased compared with before treatment, and the observation group decrease more statistically ( P < 0. 05 );there were 2 cases of dizzi-ness in the observation group and 1 in the control group, with no statistically significant difference ( P > 0. 05 ) . Conclusion The polyene phosphatidyl choline combined with adenosine methionine in treating alcoholic cirrhosis of the liver can significantly improve the clinical efficacy and liver function, inhibit or reverse the occurrence of liver fibrosis with no adverse reactions, which is worthy of clini-cal and promotion.关键词
多烯磷脂酰胆碱/腺苷蛋氨酸/酒精性肝硬化/肝功能/肝纤维化Key words
polyene phosphatidyl choline/adenosine methionine/alcoholic liver cirrhosis/liver function/liver fibrosis分类
医药卫生
