中国药业2015，Vol.24Issue(23)：46-48,3.
抗生素不同给药方式治疗呼吸机相关性肺炎的临床观察
Different Ways of Antibiotic Administration in Treating Ventilator-Associated Pneumonia
王昕华 1赵弘卿1
作者信息
- 1. 江苏省无锡市第二人民医院呼吸科,江苏 无锡 214002
- 折叠
摘要
Abstract
Objective To investigate the clinical effect and safety of intravenous antibiotics combined with aerosol inhalation and intra-venous antibiotics in the treatment of ventilator-associated pneumonia. Methods 60 patients from June 2012 to June 2014 were randomly divided into the observation group and the control group, 30 cases in each group. The observation group was treated with intravenous antibiotics combined with aerosol inhalation, while the control group was treated with intravenous antibiotics only. 7 d for 1 course of treatment. Results The temperature and WBC number of the observation group were significantly reduced compared with the control group at 7 d and 14 d after treatment ( P < 0. 05 ) , and the mean treatment time of the observation group were shorter than the control group ( P < 0. 05 ); the sputum culture negative rate and clinical cure rate were significantly increased compared with the control group after two weeks of treatment ( P < 0. 05 );the death rate and recurrence rate showed no statistical differences between two groups ( P > 0. 05 );no serious adverse reaction happened during treatment in two groups. Conclusion Patients treated with intravenous antibiotics combined with aerosol inhalation has a faster improvement of symptoms, a higher clinical cure rate, and a shorter treatment time with better security. It is effective in treatment of ventilator-associated pneumonia.关键词
呼吸机相关性肺炎/静脉给药/雾化吸入/抗生素Key words
ventilator-associated pneumonia ( VAP )/intravenous/aerosol inhalation/antibiotics分类
医药卫生引用本文复制引用
王昕华,赵弘卿..抗生素不同给药方式治疗呼吸机相关性肺炎的临床观察[J].中国药业,2015,24(23):46-48,3.
