中国药业2015，Vol.24Issue(23)：171-172,2.
紫杉醇联合卡铂不同给药途径治疗卵巢癌的疗效观察
Two Dosage Regimens of Paclitaxel Combined with Carboplatin in Treating Ovarian Cancer
曾凡清 1吴南顺 1殷娟 1张蕾1
作者信息
- 1. 重庆市第九人民医院妇科,重庆 400700
- 折叠
摘要
Abstract
Objective To investigate the effect of two dosage regimens of paclitaxel combined with carboplatin in treating ovarian can-cer. Methods The clinical data of 65 patients with ovarian cancer from May 2010 to May 2012 were analyzed. Among them, 33 pa-tients received Ⅳ regimen and 32 patients received IP+Ⅳ regimen. Short term clinical efficacy and adverse reactions of chemotherapy in two groups were observed. Results The effective rate in Ⅳ group and IP+Ⅳ were 63. 64% and 87. 50% respectively ( P < 0. 05 ) . The marrow depression in IP+Ⅳ group were significantly lower than that in Ⅳ group. The damage of gastrointestinal tract and liver function in IP+Ⅳ group was significantly higher than that in Ⅳ group ( P < 0. 01 ) . Conclusion Intraperitoneal infusion with paclitaxel plus carboplatin is an effective way in treating ovarian cancer.关键词
卵巢癌/紫杉醇/卡铂Key words
ovarian cancer/paclitaxel/carboplatin分类
医药卫生引用本文复制引用
曾凡清,吴南顺,殷娟,张蕾..紫杉醇联合卡铂不同给药途径治疗卵巢癌的疗效观察[J].中国药业,2015,24(23):171-172,2.
