重庆医学Issue(2)：173-175,179,4.DOI:10.3969/j.issn.1671-8348.2016.02.009
TACE联合HIFU治疗老年原发性肝癌的临床研究
Transarterial chemotherapy embolization combined with high intensity focused ultrasound for treating elderly patients with primary liver cancer
摘要
Abstract
Objective To evaluate clinical therapeutic efficacy of transarterial chemotherapy embolization (TACE) combined with high intensity focused ultrasound (HIFU ) compared with single TACE for treating elder patients ( ≥ 60 years old) with pri-mary liver cancer .Methods Clinical data of 72 elderly patients with primary liver cancer in the Second Affiliated Hospital of Chongqing Medical University were retrospectively analyzed .They were divided into TACE combined with HIFU group (combina-tion group :n= 36) and TACE group (TACE group :n= 36) according to the treatment .Compared tumor shrunk ,the change of AFP value and liver function ,median survival time ,1 year ,2 years ,3 year survival rates in two groups .Results The degree of tumor shrunk in combination group were more significant than that of TACE group (P< 0 .05) ,meanwhile ,AFP value decreased more in combination group (P< 0 .05) .Median survival time in combination and TACE group ,the 1 year ,2 years ,3 year survival rates were (32 .0 ± 6 .9) months ,83 .1% ,57 .3% ,42 .6% and (21 .0 ± 6 .3) months ,62 .9% ,41 .4% ,22 .3% respectively ,as compared with the TACE group ,the combination group had a higher survival rate (P< 0 .05) .There were no severe complications in both groups .Con-clusion The treatment of TACE combined with HIFU is effective and safe for treating elder patients with primary liver cancer and can make more clinical benefits compared with single TACE .关键词
老年人/肝肿瘤/经动脉化疗栓塞术/高强度聚焦超声Key words
the elderly/liver neoplasms/transarterial chemotherapy embolization/high intensity focused ultrasoun分类
医药卫生引用本文复制引用
龚文,李文仿,冉立峰,朱辉,李生伟,龚建平..TACE联合HIFU治疗老年原发性肝癌的临床研究[J].重庆医学,2016,(2):173-175,179,4.基金项目
国家自然科学基金资助项目（81272570）；重庆市卫生局科学基金会重点项目（2012-1-040）。 （）
