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老年女性患者骨代谢指标异常与冠心病的相关性研究

郜攀 唐刚 龙军 卢婷 肖航 司良毅

重庆医学Issue(3):348-350,3.
重庆医学Issue(3):348-350,3.DOI:10.3969/j.issn.1671-8348.2016.03.019

老年女性患者骨代谢指标异常与冠心病的相关性研究

Association of abnormal bone metabolism markers and risk of coronary heart disease in elder women patients

郜攀 1唐刚 1龙军 1卢婷 1肖航 1司良毅1

作者信息

  • 1. 第三军医大学附属西南医院老年病科,重庆400038
  • 折叠

摘要

Abstract

Objective To explore the correlation of bone metabolism levels and risk of coronary heart disease in elder women patients .Methods A total of 163 elder women patients were divided into three group:CON group ,CAD group ,and CHD group .We explored related atherosclerosis risk factors and factors related to bone metabolism .Results Compared with CON group ,there was no statistical significance in CAD group in factors related to bone metabolism(P>0 .05) .In CHD group ,serum 25‐OH‐Vitamin D significantly decreased and β‐C‐terminal telopeptide of type Ⅰ collagen significantly increased compared with CON group(P<0 .05) .Compared with CAD group ,the serum 25‐OH‐Vitamin C also significantly decreased andβ‐C‐terminal telopeptide of type Ⅰcollagen significantly increased(P< 0 .05) .Spearman correlation analysis showed that BMI ,HDL‐C ,triglycerides ,LDL‐C ,blood glucose and 25‐OH‐Vitamin D were correlated with coronary heart disease .With coronary heart disease as the dependent variable , the results showed lower LDL‐C ,25‐OH‐Vitamin D had independent predictive value for the risk coronary heart disease .Conclusion Lower 25‐OH‐Vitamin D levels in elder patients were positively correlated with coronary heart disease ,and it might also be an in‐dependent predictor .

关键词

老年人/妇女/冠心病/骨代谢

Key words

aged/women/coronary heart disease/bone metabolism

分类

医药卫生

引用本文复制引用

郜攀,唐刚,龙军,卢婷,肖航,司良毅..老年女性患者骨代谢指标异常与冠心病的相关性研究[J].重庆医学,2016,(3):348-350,3.

基金项目

国家自然科学基金资助项目(81370446)。 ()

重庆医学

OA北大核心

1671-8348

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