动物医学进展Issue(2)：85-90,6.
牛传染性鼻气管炎疫苗研究进展
Advance in Vaccines of Infectious Bovine Rhinotracheitis
摘要
Abstract
Infectious bovine rhinotracheitis (IBR)is a feverish and contagious infectious disease of cattle caused by infectious bovine rhinotracheitis virus (IBRV).Since it lacks effective therapeutic drugs,vaccine immunization is an ideal approach against IBR.Currently available vaccines against IBR are modified live attenuated virus (MLV)and killed whole virus (KV).Because the gene-deleted vaccines incorporate im-munological markers,they have become a new trend for the new vaccine research and development.Some developed countries have used gene deleted marker vaccines like IBRV gE-deleted marker vaccines to im-plement successfully IBR control and eradication plan.However,the existent live vaccines exhibit immune suppression to some extent.Therefore,more effective vaccines are urgently needed.This paper reviewed IBRV immunological properties,immune suppression and the recent researchs on IBRV vaccines in order to provide reference for development of more effective vaccines and IBRV control.关键词
牛传染性鼻气管炎/牛疱疹病毒Ⅰ型/疫苗/流行/防控Key words
Infectious bovine rhinotracheitis/Bovine herpes virus type 1/vaccine/prevalence/prevention and control分类
农业科技引用本文复制引用
刘瑞宁,邓明亮,刘玉辉,陈颖钰,郭爱珍..牛传染性鼻气管炎疫苗研究进展[J].动物医学进展,2016,(2):85-90,6.基金项目
农业公益性行为科研专项(201003060) （201003060）
现代农业(肉牛)产业技术体系专项资金(CARS-38) （肉牛）
