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聚合物在荧光检测领域的应用

宋春霞 羊小海 王柯敏 王青 刘剑波 黄晋 李文山 黄海花 刘卫

高等学校化学学报Issue(2):201-212,12.
高等学校化学学报Issue(2):201-212,12.DOI:10.7503/cjcu20150796

聚合物在荧光检测领域的应用

Application of Polymers in Fluorescence Analysis†

宋春霞 1羊小海 1王柯敏 1王青 1刘剑波 1黄晋 1李文山 1黄海花 1刘卫1

作者信息

  • 1. 湖南大学化学生物传感与计量学国家重点实验室,化学化工学院,生物纳米与分子工程湖南省重点实验室,长沙 410082
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摘要

Abstract

Polymers are macromolecular compounds built up from single or numerous kinds of monomers. The common materials in production and living ( for example protein, nucleic acid, starch, fiber, plastic and rubber, etc. ) are included in this category. Owing to the unique properties after polymerization and their monomers, polymers have been extensively used in fluorescence analysis as fundamental materials: target recognition can be realized through polymers interact with target molecules through intermolecular forces (hydrogen bond, hydrophilic and hydrophobic function, and van der Waals’ force, etc. ); certein polymers can transform the molecular recognition event to easily recognizable fluorescence signal, and then fluorescence signal transformation and amplification could be realized; certein polymers have been used as framework of flourescence probes, therefore the recognition capacity of fluorescence probes are improved due to multivalency effect, and multifunction devices are constructed based on the conjugation of different functional units. In this paper, the research and application of polymers in molecular recognition, signal transformation and as frame-work of probes were reviewed.

关键词

聚合物/荧光检测/分子识别/信号转换/探针骨架

Key words

Polymer/Fluorescence analysis/Molecular recognition/Signal transduction/Framework of fluorescence probe

分类

化学化工

引用本文复制引用

宋春霞,羊小海,王柯敏,王青,刘剑波,黄晋,李文山,黄海花,刘卫..聚合物在荧光检测领域的应用[J].高等学校化学学报,2016,(2):201-212,12.

基金项目

国家自然科学基金(批准号:21190040,21175035)和国家“九七三”计划项目(批准号:2011CB911002)资助.? Supported by the National Natural Science Foundation of China(Nos.21190044,21175035) and the National Basic Research Program of China(No.2011CB911002) (批准号:21190040,21175035)

高等学校化学学报

OA北大核心CSCDCSTPCD

0251-0790

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