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CDX2、survivin在半鸡皮样改变大肠腺瘤中的表达情况

韩丹 关景明

国际医药卫生导报2016,Vol.22Issue(4):457-459,463,4.
国际医药卫生导报2016,Vol.22Issue(4):457-459,463,4.DOI:10.3760/cma.j.issn.1007-1245.2016.04.005

CDX2、survivin在半鸡皮样改变大肠腺瘤中的表达情况

Expressions of CDX2 and survivin in colorectal adenoma with chicken-skin mucosa

韩丹 1关景明2

作者信息

  • 1. 110031 沈阳市第四人民医院
  • 2. 150001 哈尔滨医科大学附属第二医院
  • 折叠

摘要

Abstract

Objective To explore the relationship of CDX2 and survivin with cancerous adenoma and the clinical significance of colorectal adenoma with chicken-skin mucosa (CSM).Methods The expressions of CDX2 and survivin in normal colorectal mucosa,colorectal adenoma with CSM,colorectal adenoma without CSM and colorectal adenocarcima were detected by RT-PCR and immunohistochemistry SP.Results There were no statistical differences in the expressions of CDX2 and survivin between colorectal adenoma with CSM and colorectal adenocarcima (P>0.05) but were between colorectal adenoma and normal colorectal tissue (P<0.01).Conclusions CDX2 and survivin participate the process of adenoma canceration together.Colorectal adenomas with CSM is more cancerating than that without CSM.

关键词

CDX2/survivin/大肠腺瘤/鸡皮样粘膜/癌变

Key words

CDX2/Survivin/Colorectal adenoma/Chicken-skin mucosa/Canceration

引用本文复制引用

韩丹,关景明..CDX2、survivin在半鸡皮样改变大肠腺瘤中的表达情况[J].国际医药卫生导报,2016,22(4):457-459,463,4.

国际医药卫生导报

1007-1245

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