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结核疫苗的研究进展

李莘(综述) 王咏梅(审校)

临床与病理杂志Issue(1):85-88,4.
临床与病理杂志Issue(1):85-88,4.DOI:10.3978/j.issn.2095-6959.2016.01.016

结核疫苗的研究进展

Research progress of mycobacterium tuberculosis and vaccination

李莘(综述) 1王咏梅(审校)1

作者信息

  • 1. 天津市海河医院病理科,天津市呼吸疾病研究所,国家中医药管理局中医药防治传染病重点研究室,天津 120000
  • 折叠

摘要

Abstract

Tuberculosis is a kind of epidemic disease caused by the bacteriummycobacterium tuberculosis (Mtb). Mtb was discovered by Robert Koch in 1882, remains a leading cause of mortality worldwide. What is more, the morbidity of MDR and XDR Mtb is increasing. Tuberculosis is a global emergency announced by The World Health Organization (WHO) in last 90s. The best prevention is receiving vaccine, butMycobacterium bovis bacille Calmette-Guérin (BCG) does not have a whole protective effect in adults. Atfer theM.tuberculosis genome was published, great improvements are attained as several vaccine candidates are in the clinical trial process, such as recombinant BCGs, subunit vaccines. hTis article will do a review concerning these respects.

关键词

结核病/疫苗/卡介苗

Key words

tuberculosis/vaccine/bacille Calmete-Guérin (BCG)

引用本文复制引用

李莘(综述),王咏梅(审校)..结核疫苗的研究进展[J].临床与病理杂志,2016,(1):85-88,4.

临床与病理杂志

OACSTPCD

1673-2588

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