广西医学Issue(1)：71-73,3.DOI:10.11675/j.issn.0253-4304.2016.01.22
阿托伐他汀钙强化治疗对动脉粥样硬化脑梗死患者血脂水平及颈动脉斑块的影响
Effect of intensive treatment with atorvastatin calcium on blood lipid level and carotid artery plaque in patients with atherosclerotic cerebral infarction
吴霖浦1
作者信息
- 1. 广西桂林市人民医院神经内科，桂林市 541002
- 折叠
摘要
Abstract
Objective To explore the effect of intensive treatment with atorvastatin calcium on blood lipid level and carotid artery plaque in patients with atherosclerotic cerebral infarction .Methods A total of 92 patients with atherosclerotic cerebral infarction were enrolled and were divided into observation group ( n=46 ) and control group ( n=46 ) by random number table .The diet control was performed in both groups.And control group was administered atorvastatin calcium with normal dose (10 mg/d),while observation group received intensive treatment with atorvastatin calcium (40 mg/d).The blood lipid level and carotid artery plaque were observed in both groups before and after treatment.Results After treatment,the levels of TC,TG and LDL-C were significantly lower,and the plaque size, plaque thickness and carotid artery intima-media thickness(IMT) were less in both groups(P<0.05),and those indicators in the observation group improved more significantly compared to the indicators in the control group (P<0.05).The level of HLD-C increased in both groups after treatment(P<0.05),and the level in the observation group was significantly higher than that in the control group (P<0.05). Conclusion Atorvastatin calcium with intensive dose can improve effectively the abnormity of blood lipid and carotid artery plaque in patients with atherosclerotic cerebral infarction .关键词
动脉粥样硬化/脑梗死/阿托伐他汀钙/强化治疗/血脂/颈动脉斑块Key words
Atherosclerosis/Cerebral infarction/Atorvastatin calcium/Intensive treatment/Blood lipid/Carotid artery plaque分类
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吴霖浦..阿托伐他汀钙强化治疗对动脉粥样硬化脑梗死患者血脂水平及颈动脉斑块的影响[J].广西医学,2016,(1):71-73,3.
