中国实用神经疾病杂志Issue(2)：1-3,3.
药物结合心理行为治疗精神分裂症伴代谢综合征的效果分析
The effective analysis of schizophrenia complicated with metabolic syndrome treated by medication and psycho-behavior therapy
摘要
Abstract
Objective To explore the effects of medication and psycho-behavior therapy on schizophrenia complicated with metabolic syndrome.Methods One hundred schizophrenia Patients complicated with metabolic syndrome were randomly divided into intervention group and control group,50 cases in each group.In addition to ziprasidone antipsychotic medication for both groups,the intervention group received psycho-behavior therapy for 6 months.The positive and negative symptom scale (PAN-SS)was performed to assess curative effect,and general quality of life inventory (GQOLI-74)was used to evaluate physical function,psychological function and social function.At the same time,the rate of recurrence and readmission was comparatively analyzed between two groups.Results There was no significant difference between two groups before treatment in terms of PANSS scores,GQOLI-74 scores and abnormal metabolic scores (P >0.05 ),all of which were obviously improved after 6-month therapy in both groups (P < 0.05 );Furthermore,after therapy,and the intervention group got the higher scores of physical function and psychological function,higher PANSS scores and less abnormal metabolic scores compared with control group (all P <0.05).The rate of recurrence and rate of readmission observed within 6 months in intervention group were 10%(5 cases)and 8% (4 cases),which were significantly lower than 26% (13 cases),22% (1 1 cases)observed in the control group with statistically significant differences (χ2 = 4.33,3.84;P < 0.05 ).Conclusion The therapy of medication combined with psycho-behavior therapy can significantly improve the therapeutic effects and metabolic indicators to improve the quality of life and reduce the rate of recurrence and readmission in schizophrenia patients complicated with metabolic syndrome.关键词
精神分裂症/代谢综合征/齐拉西酮/心理行为治疗Key words
Schizophrenia/Metabolic syndrome/Ziprasidone/Psycho-behavior therapy分类
医药卫生引用本文复制引用
钟远惠,袁日强,刘舜华,周平,谢穗峰..药物结合心理行为治疗精神分裂症伴代谢综合征的效果分析[J].中国实用神经疾病杂志,2016,(2):1-3,3.基金项目
梅州市科技局计划项目(项目编号:2012B115) （项目编号:2012B115）
