湖南中医药大学学报2016，Vol.36Issue(2)：44-46,3.DOI:10.3969/j.issn.1674-070X.2016.02.012
不同助溶剂作用下桉叶油对痤疮丙酸杆菌的作用
Study of Eucalyptus Oil with Different Cosolvent on Propionibacterium acnes
摘要
Abstract
Objective To observe eucalyptus oil with different cosolvent on Propionibacterium acnes(P. acnes) and provide certain references for the treatment of acne, at the same time provide the support for the development and utilization of eucalyptus oil resources. Methods The eucalyptus oil with different cosolvent on bacillus bacteriostatic ring diameter and the minimum bacteriostasis concentration of acne propionic acid were observed by using tablet Oxford cup method and test tube method. Results 80% pure eucalyptus oil, 40% eucalyptus oil ethanol solution and 40% eucalyptus oil acetone solution show completely bacteriostatic action on P. acnes, there is no bacterial growth on tablet. The average bacteriostatic circle positive control medicine (16 ug/mL erythromycin) on P. acnes was 29.44 mm; Cosolvent 95% ethanol and acetone didn't show bacteriostatic action on P. acnes; Blank control (distilled water) had no bacteriostatic action on P. acnes. When acetone as cosolvent, the minimal inhibitory concentrations (MIC) of eucalyptus oil was 0.625%; When 95% ethanol as cosolvent, the MIC of eucalyptus oil was 1.25%. Conclusion Eucalyptus oil show good bacteriostasis on P. acnes. The cosolvent 95%ethanol and acetone didn't exhibit bacteriostatic action. Cosolvent has a certain influence on the MIC of eucalyptus oil, when acetone as cosolvent the minimum bacteriostasis concentration was lower than 95% ethanol as cosolvent.关键词
桉叶油/助溶剂/乙醇/丙酮/痤疮丙酸杆菌/抑菌作用/最低抑菌浓度Key words
eucalyptus oil/cosolvent/alcohol/acetone/Propionibacterium acnes/bacteriostatic action/minimum bacte-riostasis concentration分类
医药卫生引用本文复制引用
杨柳,胡彬,谢遥,蒋丹,朱明芳..不同助溶剂作用下桉叶油对痤疮丙酸杆菌的作用[J].湖南中医药大学学报,2016,36(2):44-46,3.基金项目
湖南省科技厅项目(2014SK4051) （2014SK4051）
湖南省教育厅基金项目(13B086). （13B086）
