天津中医药Issue(2)：114-117,4.DOI:10.11656/j.issn.1672-1519.2016.02.14
淫羊藿化学成分分离鉴定
Isolation and identification of chemical constituents from Epimedium brevicornu Maxim
摘要
Abstract
Objective] To investigate chemical constituents from the leave of Epimedium brevicornu Maxim. [Methods] The compounds were purified by solvents extracting and several column chromatography, including silica gel, Sephadex LH-20, ODS and preparative HPLC. Their structures were identified by MS and NMR spectra. [Results] Seven compounds were separated from 95% ethanol (V/V) extract of E. brevicornu and identified as 2,3,5,6,7-pentamethoxy-phenanthrene (1), 4,5-dihydroxy-2,3,6-trimethoxy-9,10-dihydrophenanthrene (2), 5,7,4'-trimethoxy-4-phenylcoumarin (3), 3,5,7,4'-tetramethoxyflavone (4), 4-hydroxy-3-prenylbenzoic acid (5), 4-Hydroxycinnamic acid methyl ester (6), and (2E)-2-nonenoic acid, 4-hydroxy (7). [Conclusion] Compound 1~7 were obtained from genus of Epimedium for the first time.关键词
淫羊藿/化学成分/结构鉴定Key words
Epimedium brevicornu Maxim./chemical constituent/structural identification分类
医药卫生引用本文复制引用
柴士伟,刘芳..淫羊藿化学成分分离鉴定[J].天津中医药,2016,(2):114-117,4.基金项目
天津市高等学校科技发展基金一般资助项目（20120203）。 （）
