中国组织工程研究Issue(52)：8396-8400,5.DOI:10.3969/j.issn.2095-4344.2015.52.006
骨水泥和纳米骨浆强化椎弓根螺钉植入固定骨质疏松椎体的生物力学特点
Bone cement and nano bone putty strengthen pedicle screw implantation in the fixation of osteoporotic vertebral body：biomechanical characteristics
摘要
Abstract
BACKGROUND:Nano bone putty and bone cement injection are two common methods to strengthen the fixation of pedicle screws, but there are relatively few reports on the comparison of their strengthening effects. OBJECTIVE:To compare the biomechanical characteristics of bone cement and nano bone putty strengthening pedicle screw implantation in the fixation of osteoporotic vertebral body. METHODS: Totaly 24 human cadaveric pedicles were obtained, which were al in line with osteoporosis standards, and randomly divided into 3 groups: control group (only implanted pedicle screws), bone cement group (first injected bone cement in the nail channel, and then implanted pedicle screws) and nano bone putty group (first injected nano bone putty in the nail channel, and then implanted pedicle screws). After 2 hours of implantation, the maximum axial pulout strength and the maximum rotation torque of specimens in each group were determined. RESULTS AND CONCLUSION:The maximum axial pulout strength and maximum rotation torque of the bone cement and the nano bone putty groups were greater than those of the control group (P < 0.05), and the maximum axial pulout strength and the maximum rotation torque of the bone cement group were greater than those of the nano bone putty group (P < 0.05). These results demonstrate that the maximum axial pulout strength and the maximum rotation torque of pedicle screw implantation in the fixation of osteoporotic vertebral body can be effectively improved by injection of bone cement and nano bone putty, and the strengthening effect of bone cement is more obvious. 关键词
生物材料/骨生物材料/椎弓根螺钉/骨水泥/纳米骨浆/骨质疏松/加强/生物力学/稳定性分类
医药卫生引用本文复制引用
卢小兵,孟祥翔..骨水泥和纳米骨浆强化椎弓根螺钉植入固定骨质疏松椎体的生物力学特点[J].中国组织工程研究,2015,(52):8396-8400,5.基金项目
浙江大学CAD&CG国家重点实验室开放课题(A1405)面向骨科植入物设计的三维骨骼几何分析Funding：Open Project of CAD & CG State Key Laboratory in Zhejiang University of China, No. A1405 （A1405）
