中国组织工程研究Issue(52)：8418-8422,5.DOI:10.3969/j.issn.2095-4344.2015.52.010
聚醚醚酮/牙源性双相生物陶瓷复合材料的制备及力学性能
Preparation and mechanical properties of polyetheretherketone/odontogenic biphasic bioceramic composites
摘要
Abstract
BACKGROUND:The physical properties and chemical composition of teeth are very similar with human bone tissue, and there are a larger proportion of inorganic components. Therefore, tooth can be considered as a potential repair material for autologous or alogeneic bone defects. OBJECTIVE:To prepare polyetheretherketone/odontogenic biphasic bioceramic composite, and to test its mechanical properties. METHODS: The humanin vitro teeth of clinical waste were colected. The organic components were removed after a preliminary calcination. Another calcination was conducted after soaking in diammonium phosphate solution for 24 hours to prepare the biphasic ceramics with the main components of hydroxyapatite and β-tricalcium phosphate. The biphasic ceramics were ground and sieved using 200-mesh sieve folowed by impregnation in organic foam to prepare polyetheretherketone/odontogenic biphasic bioceramics. Phase analysis, scanning electron microscopy, elemental analysis, porosity, compressive strength and bond strength test were conducted. RESULTS AND CONCLUSION:Polyetheretherketone/odontogenic biphasic bioceramics presented porous network structure and interconnected holes, with the aperture of 100-800 μm, porosity of 73.65%, compressive strength of (165.260±11.703) N, bond strength of (14.63±6.21) MPa. P element content accounted for 19.8%, and Ca element content accounted for 40.5%. The main phases were β- tricalcium phosphate and hydroxyapatite. These results demonstrate that polyetheretherketone/odontogenic biphasic bioceramics have good mechanical properties.关键词
生物材料/口腔生物材料/聚醚醚酮/牙源性双相生物陶瓷复合材料/制备/骨组织力学性能/羟基磷灰石/β-磷酸三钙/国家自然科学基金分类
医药卫生引用本文复制引用
冷卫东,刘彩云,黄翠,艾俊,石从郁,余和东..聚醚醚酮/牙源性双相生物陶瓷复合材料的制备及力学性能[J].中国组织工程研究,2015,(52):8418-8422,5.基金项目
国家自然科学基金应急管理项目(51541202)3-D打印双管道骨修复生物复合材料的构建及相关机理研究；湖北省卫生和计划生育委员会一般项目(2015MB289)聚醚醚酮/牙源性双相生物陶瓷复合材料的应用基础研究 Funding:the National Natural Science Foundation of China, No.51541202 （51541202）
General Program of Health and Family Planning Commission of Hubei Province of China, No.2015MB289 （）
