中国感染控制杂志Issue(1)：22-25,4.DOI:10.3969/j.issn.1671-9638.2016.01.005
肾盂肾炎患者经验用抗菌药物与药敏结果符合率
Coincidence rates between empiric antimicrobial use and antimicrobial sus-ceptibility testing results in patients with pyelonephritis
张海谱 1梁霞 1贾克然 1赵会海 1史文俊 2王缚鲲1
作者信息
- 1. 石家庄市白求恩国际和平医院，河北 石家庄 050082
- 2. 邯郸市解放军 285 医院，河北 邯郸 056001
- 折叠
摘要
Abstract
Objective To understand the empiric antimicrobial use in patients with pyelonephritis in a hospital,and pro-vide reference for clinical rational antimicrobial use.Methods Data of 620 patients with pyelonephritis admitted to the nephrology department of a hospital between January 2011 and September 2014 were collected,application of antimicrobial agents,coincidence between empiric antimicrobial use and antimicrobial susceptibility testing results in patients with different diseases and different ages were analyzed.Results Before antimicrobial susceptibility testing results were reported,620 pa-tients use 625 times of antimicrobial agents,5 of whom used two kinds of antimicrobial agents at the same time,8 varieties in 15 types of antimicrobial agents were involved,the most frequently used antimicrobial agents were third generation ceph-alosporins,cephamycins,and fluoroquinolones.The overall,partial,and non-coincidence rate between antimicrobial use and antimicrobial susceptibility testing results were 64.32%(n=402),8.32%(n=52),and 27.36%(n=171)respective-ly.The overall coincidence rate in patients with acute pyelonephritis was higher than those with chronic pyelonephritis (77.61% [n=357]vs 58.79%[n=97],P <0.05).The overall coincidence rate in patients <50 years old and ≥50 years old were 68.12%(156/229)and 75.25%(298/396)respectively,there was no significant different between two groups (χ2 =2.93,P =0.09).Conclusion The non-coincidence rate between empiric antimicrobial use and antimicrobial suscepti-bility testing results is high,measures needs to be taken to improve the empiric antimicrobials use.关键词
肾盂肾炎/抗菌药物/治疗/药敏分析/符合率/合理用药Key words
pyelonephritis/antimicrobial agent/treatment/antimicrobial susceptibility analysis/coincidence rate/rational drug use分类
医药卫生引用本文复制引用
张海谱,梁霞,贾克然,赵会海,史文俊,王缚鲲..肾盂肾炎患者经验用抗菌药物与药敏结果符合率[J].中国感染控制杂志,2016,(1):22-25,4.
