中国临床药理学杂志Issue(3)：283-285,3.DOI:10.13699/j.cnki.1001-6821.2016.03.028
格列苯脲在人胎盘中转运机制的研究状况
Progress of glyburide transport mechanisms in the human placenta
摘要
Abstract
With the in-depth study of oral hypoglycemic drugs , the safe-ty and effectiveness of glyburide in the treatment of gestational diabetes has been confirmed.Related studies showed that glyburide had a lower placental transmission.And the studies about placental transport mecha-nisms showed that it might be associated with a variety of transport pro-teins, including ATP ( adenosine 5 ’ -triphosphate ) -binding cassette ( ABC ) transporters and organic anion transporting polypeptides ( OATPs).关键词
格列苯脲/人胎盘/磷酸化-糖蛋白/多药耐药相关蛋白/乳腺癌耐药蛋白/有机阴离子转运肽2 B1Key words
glyburide/human placenta/P-glycoprotein/multidrug re-sistance-related protein/breast cancer resistance protein/organic anion transporting polypeptide 2B1分类
医药卫生引用本文复制引用
端木雯婧,黄桦,姚勤,王晶晶,郑巧玲,张峻..格列苯脲在人胎盘中转运机制的研究状况[J].中国临床药理学杂志,2016,(3):283-285,3.基金项目
国家自然科学地区基金资助项目（81360108）；云南省科技厅昆明医科大学应用基础研究联合专项基金资助项目（2013FB139）；云南省医疗卫生单位内设研究机构建设计划基金资助项目 （）
