中国全科医学Issue(4)：474-478,5.DOI:10.3969/j.issn.1007-9572.2016.04.025
上海市浦东新区社区2型糖尿病患者糖尿病性视网膜病变的患病情况及影响因素调查
Prevalence of Diabetic Retinopathy of Type 2 Diabetes Mellitus Patients in Shanghai Pudong New Area and Influencing Factors
摘要
Abstract
Objective To investigate the prevalence of diabetic retinopathy( DR)of type 2 diabetes mellitus (T2DM)patients in Shanghai Pudong New Area community and its influencing factors. Methods A total of 2 083 T2DM patients included in the management of community health service centers selected in Shanghai Pudong New Area were enrolled from May 2014 to February 2015. The fundus lesions of patients were classified into non - obvious diabetic retinopathy(NDR),mild non -proliferative diabetic retinopathy(NPDR),moderate NPDR and severe NPDR and proliferation diabetic retinopathy(PDR)by figure nonmydriatic fundus photographs. Basic information,physical examination indicators and laboratory examination indexes of different DR patients were compared and analysed. Results The DR prevalence of 2 083 patients was 21. 4% (445 / 2 083);and the prevalence of patients with mild NPDR,moderate NPDR and severe NPDR and PDR were 14. 3(297 / 2 083),2. 9%(60 / 2 083),4. 2% (88 / 2 083)respectively. The difference of DR prevalence among different streets was not significant(P >0. 05). Patients with different DR conditions were not significantly different in gender,body mass index(BMI),waist - hip ratio( WHR),systolic blood pressure( SBP),diastolic blood pressure( DBP),total cholesterol( TC),triacylglycerol (TG),low density lipoprotein cholesterin( LDL-C),high density lipoprotein cholesterol( HDL-C) and urine creatinine (UCr) (P > 0. 05);while patients with different DR conditions were significantly different in average age,average disease duration,average onset age, fasting blood - glucose ( FPG ), postprandial blood glucose 2 h ( 2 hPG ), glycosylated hemoglobin(HbA1c ),urine microalbumin( UMA)and urinary albumin to creatinine ratio( ACR) ( P < 0. 05). Logistic stepwise regression analysis showed that the effect of disease course,onset age,2 hPG and HbA1c on DR in T2DM patients was significant(P < 0. 05). Conclusion The DR prevalence rate of T2DM patients in Shanghai Pudong New Area community is lower than that of previous studies,with non - proliferative diabetic retinopathy as the main lesion. Disease course,onset age,2 hPG and HbA1c are influencing factors for DR in T2DM patients.关键词
糖尿病,2 型/糖尿病视网膜病变/患病率/影响因素分析Key words
Diabetes mellitus,type 2/Diabetic retinopathy/Prevalence/Root cause analysis分类
医药卫生引用本文复制引用
梁辰,沙天宇,施榕,朱静芬,张胜冰,宋道平,陈黎,贾丽丽,冯易,杨辉..上海市浦东新区社区2型糖尿病患者糖尿病性视网膜病变的患病情况及影响因素调查[J].中国全科医学,2016,(4):474-478,5.基金项目
上海市公共卫生重点学科（全科医学）建设项目 （）
