中国现代医学杂志Issue(2)：64-67,4.DOI:10.3969/j.issn.1005-8982.2016.02.014
妊娠糖尿病患者白细胞介素6、肿瘤坏死因子α及脂联素水平及其相关性研究*
Correlation of gestational diabetes with IL-6, TNF-alpha and ADP
摘要
Abstract
Objective To explore the level of interleukin 6 (IL-6), tumor necrosis factor alpha (TNF-α) and adiponectin (ADP) in pregnant patients with gestational diabetes mellitus, and its relationship with related in-dicators. Methods Forty cases with gestational diabetes in our hospital from January 2013 to January 2014 were selected as the study group, 40 cases of healthy pregnant women during the same period for health ex-amination were selected as the control group. Serum IL-6, TNF-α and ADP levels of the two groups were tested and compared. Correlations of the above indexes with fasting blood glucose (FBG), fasting insulin (FINS), body mass index (BMI) and insulin resistance (IR) were researched. Results The differences in mater-nal IL-6, TNF-α, ADP and IR levels were statistically significant between the two groups ( <0.05). Both IL-6 and TNF-α had positive correlations with FINS, BMI and IR ( <0.05). There was no correlation among other indicators ( >0.05). Conclusions IL-6 and TNF-α levels of pregnant women with gestational diabetes are significantly higher than those of normal pregnanct women, ADP is significantly lower than that of normal pregnanct women. IL-6 and TNF-α are correlated with IR, and can be important indexes in detection and diagnosis of gestational diabetes mellitus.关键词
妊娠期糖尿病/白细胞介素- 6/肿瘤坏死因子α/血清脂联素/相关性Key words
gestational diabetes/interleukin 6/tumor necrosis factor alpha/serum adiponectin/correlation分类
医药卫生引用本文复制引用
欧武英,李闻文,叶芳丽..妊娠糖尿病患者白细胞介素6、肿瘤坏死因子α及脂联素水平及其相关性研究*[J].中国现代医学杂志,2016,(2):64-67,4.基金项目
海南省卫生厅医学科研项目 （）
