中国现代医学杂志Issue(3)：82-86,5.DOI:10.3969/j.issn.1005-8982.2016.03.017
鼻咽癌放疗抵抗的分子机制研究进展*
Research progress on molecular mechanism of nasopharyngeal carcinoma radioresistance
摘要
Abstract
Nasopharyngeal carcinoma is one of the most common malignant tumors in South China and Southeast Asia. Its morbidity and mortality are the highest among the head and neck cancers. The preferred treatment for nasopharyngeal carcinoma is radiotherapy; however, radioresistance leading to local recurrence has become a major obstacle to successful treatment. To reduce the radioresistance of patients with nasopha-ryngeal carcinoma and enhance the radiosensitivity, molecular mechanism of nasopharyngeal carcinoma radiore-sistance becomes the focus of medical researches at present. In recent years, scholars have carried out a lot of researches on the causes and mechanisms of nasopharyngeal carcinoma radioresistance in the aspects of genomics, proteomics and microRNA. This paper reviews the progress of the molecular mechanism of nasopha-ryngeal carcinoma radioresistance.关键词
鼻咽癌/放疗抵抗/基因组学/蛋白质组学/Micro RNAKey words
nasopharyngeal carcinoma/radiotherapy resistance/genomics/proteomics/microRNA分类
医药卫生引用本文复制引用
曾谷清,黄丽芳(综述),廖力(审校)..鼻咽癌放疗抵抗的分子机制研究进展*[J].中国现代医学杂志,2016,(3):82-86,5.基金项目
国家自然科学基金（No81272959；81470130）；南华大学研究生科研创新项目 （）
