中国医学创新Issue(36)：30-32,3.DOI:10.3969/j.issn.1674-4985.2015.36.010
奥氮平与利培酮治疗系统性红斑狼疮所致精神障碍疗效对照分析
Effect Comparative Analysis of Olanzapine and Risperidone in the Treatment of Mental Disorder Caused by Systemic Lupus Erythematosus
摘要
Abstract
Objective:To investigate the efficacy and safety of Olanzapine and Risperidone on mental disorder caused by lupus erythema.Method: 64 patients with mental disorders due to systemic lupus erythematosus were divided into two groups,they were treated with Olanzapine and Risperidone for 4 weeks.The efficacy before treatment and after treatment 1week, 2, 3, 4 weeks were evaluated by PANSS scale,the adverse reactions were evaluated by TESS scale.Result:After treatment for 1 week,PANSS scores of the Olanzapine group were dropped significantly,the effect was faster than the Risperidone group,the curative effect difference of the two groups was statistically significant (P<0.01). The adverse reactions of the Olanzapine group were lower than those of the Risperidone group, the differences were statistically significant (P<0.01).Conclusion: Olanzapine and Risperidone on mental disorders caused by lupus erythematosus are effective, and Olanzapine work faster, with less adverse reaction, more suitable for patients with mental disorder caused by lupus erythematosus.关键词
系统性红斑狼疮/精神障碍/奥氮平/利培酮Key words
Systemic lupus erythematosus/Mental disorder/Olanzapine/Risperidone引用本文复制引用
叶庆红,陈志斌,唐锴,杨敏,张东平..奥氮平与利培酮治疗系统性红斑狼疮所致精神障碍疗效对照分析[J].中国医学创新,2015,(36):30-32,3.基金项目
广西卫计委自筹课题项目 （）
