中国医学创新Issue(1)：36-39,4.DOI:10.3969/j.issn.1674-4985.2016.01.010
强化瑞舒伐他汀治疗急性ST段抬高型心肌梗死患者对造影剂肾病的防治作用
Preventive and Therapeutic Effect of Double-dose Rosuvastain on Contrast-induced Nephropathy in ;Acute Myocardial Infarction Patient with Percanetous Coronary Intervention
摘要
Abstract
Objective:To assess the preventive and therapeutic effect of rosuvastain used in acute myocardial infarction(AMI)patients during PCI perioperative period. Method:From 2012 to 2013,202 patients were divided into rosuvastain group(n=100)and control group(n=102). The rosuvastain group was treated by intake of rosuvastain 20 mg/d every night for four days(one day before and three day post operation), and 10 mg/d every night till outward. While the control group intake rosuvastain 10 mg/d every night lasted till outward. The urine crystals' count & assortment,protein/β2 microprotein ratio,blood rheology were measured pre and post operation for the next 72 h. The incidence of contrast-induced nephropathy(CIN) was simultaneously observed. Result:Baseline data were similar between the two groups. The rosuvastain group had a significantly lower incidence of CIN compared with that control group. Urine crystals' count and classification were highly related with the CIN,as well as the rosuvastain group remarkably reduced the above index. Also,the urine protein/β2 microprotein ratio,blood rheology were disclosed the same results. Conclusion:Rosuvastain could significantly reduce the CIN in the AMI-PCI patients by decreasing the urine crystal,protein/β2 microprotein ratio and improving the blood rheology.关键词
急性心肌梗死/造影剂肾病/瑞舒伐他汀/尿结晶Key words
Rosuvastain/Contrast-induced nephropathy/Acute myocardial infarction/Urine crystal引用本文复制引用
郭鹏,刘日辉..强化瑞舒伐他汀治疗急性ST段抬高型心肌梗死患者对造影剂肾病的防治作用[J].中国医学创新,2016,(1):36-39,4.基金项目
辽阳市科技立项课题 （）
