摘要
Abstract
Objective:To compare the analgesia effect of mono or combination of intrapelvic irrigation and incision infiltration with lidocaine carbonate and intravenous flurbiprofen axetil after gynecological laparoscopy. Method:Ninety patients scheduled for gynecological laparoscopy under general anesthesia were divided into three groups accrording to random number table. Control group 1 received intravenous flurbiprofen axetil 100 mg after surgery,control group 2 received intrapelvic irrigation and abdominal wounds infiltration with 0.35%lidocaine carbonate 100 mL and 0.87%lidocaine carbonate 10 mL respectively,and observation group received the combination of the control group 1 and control group 2. VAS pain score was measured at 1,4,8,12,24 h after operation. Total analgesic requirement,the first passage of flatus and incidence of nausea and vomiting within 24 hours were recorded as well as side effects such as circumoral numbness,dizziness,and tinnitus. Result:VAS scores of the observation group was significantly lower than that of the control group 1 and control group 2 at 1,4,8,12,24 h after surgery,with significant differences(P<O.05). No patient required repeated analgesia in the three groups. Conclusion:Combination of intravenous flurbiprofen axetil and intrapelvic irrigation(including wound infiltration) with lidocaine carbonate can significantly reduce the pain intensity and analgesia requirement without increasing the incidence of nausea and vomiting compared with intravenous flurbiprofen axetil or intrapelvic irrigation alone after gynecological laparoscopy.关键词
腹腔镜手术/术后镇痛/碳酸利多卡因/氟比洛芬酯Key words
Laparoscopic surgery/Postoperative analgesia/Lidocaine/Flurbiprofen axetil
