中国医学创新Issue(2)：1-4,4.DOI:10.3969/j.issn.1674-4985.2016.02.001
纤维蛋白原和血小板平均体积与急性脑梗死相关性研究
Correlation Studies of Fibrinogen and Mean Platelet Volume with Acute Cerebral Infarction
摘要
Abstract
Objective:To investigate the relationship between the fibrinogen(FIB) and mean platelet volume (MPV) with acute cerebral infarction.Method:200 patients with acute cerebral infarction and 100 healthy people for physical examination at the same period in our hospital from January 1,2015 to May 30,2015 were selected as the observation group and the control group,at the same time,according to the national institutes of health stroke scale(NIHSS) scores,the patients with acute cerebral infarction were divided into mild, moderate,severe three subgroups.The platelet and coagulation system of the observation group and the control group were compared,as well as the fibrinogen levels and platelet volume level among mild,moderate,severe subgroups were compared.Result:The content of platelet of the observation group was (198.32±54.47)×109/L, which was significantly lower than (219.41±52.13)×109/L of the control group,the mean platelet volume of the observation group was (10.16±1.44)fL,which was significantly higher than (9.12±1.31)fL of the control group,the platelet distribution width(PDW) of the observation group was (17.11±2.23)%,which was significantly higher than (16.21±0.91)% of the control group,the fibrinogen(FIB) of the observation group was (3.79±0.78)g/L,which was significantly higher than (3.25±0.41)g/L of the control group,the differences were statistically significant(P<0.05).The multi-factor Logistic regression analysis showed that MPV and FIB were independent risk factors for cerebral infarction.The differences were statistically significant in FIB level among three subgroups(P<0.05),and FIB level and the degree of the patients with mental disorders were positively correlated.Conclusion:MPV and FIB may be the important risk factors of acute cerebral infarction incidence,and FIB level is higher,the more severe of trauma patients,therefore,the detection of MPV and FIB levels changes in patients with acute cerebral infarction,has certain help to the treatment,is worthy of clinical application.关键词
纤维蛋白原水平/血小板平均体积/急性脑梗死Key words
Fibrinogen level/Mean platelet volume/Acute cerebral infarction引用本文复制引用
邓耀芳,邱观养,黄丹丹,黄国敏,韦恒宇..纤维蛋白原和血小板平均体积与急性脑梗死相关性研究[J].中国医学创新,2016,(2):1-4,4.基金项目
茂名市科技计划项目 （）
