摘要
Abstract
Objective To analyze the relationship of surgical conditions associated with the survival of pa⁃tients with early pancreatic cancer for providing a reference for home care and predicting the patients’progno⁃sis. Methods Subsets of 195 early pancreatic cancer patients collected were used to screen the potential risk factors for survival, such as age, TNM stage, gender and surgical methods. The patients’survival in different groups was analyzed by Kaplan-Meier method, Log-rank test and Cox regression analysis. Results In the 195 patients with early pancreatic cancer, the median survival time was 13.27 months (398 days), and 1 to 5 years survival rates were 32.58%, 23.27%, 18.28%, 18.28% and 18.28%. Comparing with the different groups’ median survival time, the patients with II stage were 306 days, lower than the 881 days of those with I stage(χ2=18.442,P< 0.001), the patients with palliative resection were 267 days, lower than the 460 days of those with radical excision (χ2=7.607,P=0.006), and the patients over 65 years old were 296 days, lower than those young⁃er ones whose median survival time were 461 days. There was no statistical significance in gender and address (χ2=0.271, 0.155, P=0.602,0.694). Cox multivariate regression analysis showed that, including elder and high TNM stage, patients with palliative resection had significantly lower cancer-specific survival (hazard ratio (HR)=1.755,95 % confidence interval (CI): 1.196-2.575) and all-cause survival (HR=1.752,95 % CI: 1.190-2.579) (P = 0.004). Conclusion Radical excision is an effective method to obtain a preferable survival for the pa⁃tients with early pancreatic cancer.关键词
胰腺癌/早期/手术方式/生存率Key words
Pancreatic cancer/early/surgical methods/survival rate分类
医药卫生
