中国中西医结合外科杂志Issue(1):28-31,4.DOI:10.3969/j.issn.1007-6948.2016.01.008
单用左氧氟沙星及其联用宁泌泰胶囊治疗慢性前列腺炎的药物经济学评价
Pharmacoeconomic Evaluation on Ningmitai Capsule Combined with Levofloxacin Therapy for Chronic Prostatitis
唐富荣 1余金明 1唐证 1张杰2
作者信息
- 1. 复旦大学公共卫生学院临床流行病研究中心 上海 200083
- 2. 上海海天医药科技开发有限公司 上海 200023
- 折叠
摘要
Abstract
Objective To compare the difference of the clinical efficacy therapies for chronic prostatitis be⁃tween levofloxacin and Ningmitai Capsule combined with levofloxacin, and evaluate their pharmacoeconomics. Methods Conducted database retrieval for meta analysis about the literatures which met criteria of domestic and imported levofloxacin to treat bacterial infections. Totally took clinical efficacy rate as index, to evaluate pharmacoeconomics with the cost-effectiveness method. Results The 6 random control trials(RCT) studies were retrieved, including 1383 patients; meta analysis showed that there was statistical significance as compared the combination of levofloxacin and Ningmitai Capsule, with single use of levofloxacin, merger OR = 1.28, 95%CI (1.21, 1.21). The economics evaluation results showed that the costs of combination treatment were higher than the single use of levofloxacin. Conclusion The combination of the drugs improves the clinical efficiency, reduces the adverse reactions and drug resistance. Although the treatment costs were increased, the drug combi⁃nation still has its rationality considering its indirect value.关键词
左氧氟沙星/宁泌泰/前列腺炎/Meta分析/药物经济学Key words
Levofloxacin/Ningmitai/chronic prostatitis/Meta analysis/pharmacoeconomics分类
医药卫生引用本文复制引用
唐富荣,余金明,唐证,张杰..单用左氧氟沙星及其联用宁泌泰胶囊治疗慢性前列腺炎的药物经济学评价[J].中国中西医结合外科杂志,2016,(1):28-31,4.