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提高急性缺血性卒中静脉溶栓有效性和安全性的研究进展

吴岩峰 刘庆萍 丁红

中国卒中杂志Issue(2):126-130,5.
中国卒中杂志Issue(2):126-130,5.DOI:10.3969/j.issn.1673-5765.2016.02.007

提高急性缺血性卒中静脉溶栓有效性和安全性的研究进展

Study Progress of Improvement of Safety and Efifcacy of Intravenous Thrombolysis on Acute Ischaemic Stroke

吴岩峰 1刘庆萍 1丁红1

作者信息

  • 1. 210003 南京南京医科大学第二附属医院神经科
  • 折叠

摘要

Abstract

The recombinant tissue plasminogen activator alteplase (rt-PA) is the most effective therapeutic drug used in intravenous thrombolysis for patients with acute ischaemic stroke presenting within 4.5h after symptom onset. Nevertheless, intravenous thrombolysis is accompanied with hemorrhagic transformation (HT), increased risk of symptomatic intracranial haemorrhage (sICH), poor prognosis and even deaths. Therefore, study on inlfuential factors on treatment and prognosis and improvement of efifcacy and safety of intravenous thrombolysis has important signiifcance for prognosis of patients with acute ischemic stroke.

关键词

急性缺血性卒中/静脉溶栓/重组组织型纤溶酶原激活剂/有效性/安全性

Key words

Acute ischaemic stroke/Intravenous thrombolysis/Recombinant tissue plasminogen activator/Efifcacy/Safety

引用本文复制引用

吴岩峰,刘庆萍,丁红..提高急性缺血性卒中静脉溶栓有效性和安全性的研究进展[J].中国卒中杂志,2016,(2):126-130,5.

中国卒中杂志

OACSTPCD

1673-5765

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