中国卒中杂志Issue(2)：155-160,6.DOI:10.3969/j.issn.1673-5765.2016.01.011
高分辨磁共振成像评价他汀治疗逆转颈动脉粥样硬化斑块研究进展
Study Progress of High Resolution MRI Evaluation in Regression of Carotid Atherosclerosis Induced by Statins Therapy
摘要
Abstract
Atherosclerotic plaque rupture with subsequent thrombosis could cause acute coronary or cerebrovascular events, which severely endangers human being’s health. Statins therapy could postpone and even reverse the progress of the formation of atherosclerotic plaque, however, there were no available no invasive imaging techniques to evaluate the effects of statins therapy on atherosclerotic plaques. As a newly emerging imaging technology, high resolution magnetic resonance imaging (HR-MRI) has good histological consonance and could accurately analyze carotid atherosclerotic plaque burden, and determine and quantitatively analyze tissue compositions of plaques including fibrous cap, liquid rich necrotic core (LRNC), calcification, intraplaque hemorrhage etc. Ultrasmall superparamagnetic iron oxide was used as contrast agent to evaluate the inlfammation level in the plaques with histological validation. This review summarizes the value of HR-MRI on evaluating regression of carotid atherosclerosis induced by statins therapy.关键词
高分辨磁共振成像/颈动脉/斑块/他汀治疗Key words
High resolution magnetic resonance imaging/Carotid arteries/Plaques/Statins therapy引用本文复制引用
宋昌鹏,陈步星..高分辨磁共振成像评价他汀治疗逆转颈动脉粥样硬化斑块研究进展[J].中国卒中杂志,2016,(2):155-160,6.基金项目
首都卫生发展科研专项 （）
