中华耳科学杂志Issue(4):712-714,3.DOI:10.3969/j.issn.1672-2922.2015.04.035
耳后注射甲强龙治疗突聋临床研究
Postaurieal injection of methylprednisolone as an auxiliary treatment for total hearing loss
赵群 1王英力 2王洪芹 1许鹏 1冯丽春 1兰娜2
作者信息
- 1. 沧州市中心医院耳鼻喉科
- 2. 沧州市人民医院耳鼻喉科
- 折叠
摘要
Abstract
Objective To assess the efficacy of postauricular injection of methylprednisolone in treating sudden total hearing loss. Methods Data of 48 cases of total sudden hearing loss treated by the authors from 2013 to present were collected. The cases were divided into a treatment and a control group, randomly. The treatment group received postauricular injection of methylprednisolone. The number of frequencies over 250 to 4000 Hz at which average thresholds were within useful hearing range (the“banana area”) and improve-ment of thresholds over five frequency bands (125-250 Hz, 125-500 Hz, 500-2000 Hz, 4000-8000 Hz and 250-4000 Hz) were compared between the two groups. Results The numbers of frequencies in the“banana”area were 1.5 for the treatment group and 0 for the control group (P=0.004). PTA improvements in the treat-ment group were 29.25±5.14 dB vs 14.00±4.66 dB for 125-250 Hz (P=0.028), 29.67±4.36 dB vs 14.77±4.38 dB for 125-500 Hz (P=0.021), 26.50±3.60 dB vs 16.52±3.77 dB for 500-2000 Hz, 26.00±7.04 dB vs 12.28± 2.93 dB for 4000-8000 Hz, and 26.99±3.75 dB vs 15.40±3.63dB for 250-4000 Hz, respectively. Conclusions Postauricular methylprednisolone injection is an effective therapy for sudden total hearing loss, especially for low-frequency involvement.关键词
突发性聋/给药方式/甲强龙/耳后注射Key words
Sudden hearing loss/Administration rout/methylprednisolone/Postaurieal injection分类
医药卫生引用本文复制引用
赵群,王英力,王洪芹,许鹏,冯丽春,兰娜..耳后注射甲强龙治疗突聋临床研究[J].中华耳科学杂志,2015,(4):712-714,3.