中国现代中药Issue(1)：110-113,125,5.DOI:10.13313/j.issn.1673-4890.2016.1.016
多指标综合加权评分法优选人参醇提工艺
Optimization of Ethanol Reflux Extraction Technique for Panax ginseng by Multi-index Comprehensive Weighted Score Evaluation
韩宵 1朱磊 2闫春风 3翁慧沥 4董海荣3
作者信息
- 1. 承德医学院 中药研究所，河北 承德 067000
- 2. 颈复康药业集团有限公司，河北 承德，067000
- 3. 河北省中药新辅料工程技术研究中心，河北 承德 067000
- 4. 颈复康药业集团有限公司，河北 承德，067000
- 折叠
摘要
Abstract
Objective:To optimize ethanol reflux optimal extraction technique for Panax ginseng and confirm the optimum extraction process parameters by multi index comprehensive weighted score evaluation.Methods: Orthogonal experiment method was applied to investigate ethanol concentration,extraction time,extraction times,solvent consumption and their interaction effects on ginseng alcohol extraction process.The total ginseng saponins was determined by UV and the content of ginsenoside Rg1 ,Re and Rb1 were determined by HPLC-ELSD.With transfer rate of Rg1 and Re ginsenosides, ginsenoside Rb1 ,tatal ginseng saponin yeild and the extract rate as the index,the extraction was comprehensive evaluated by using the weighted scoring method.Results:The optimum factors was 6 times of 70% ethanol,refluxing and extracting for 2 h,for 3 times.Conclusion:The optimized extraction process is simple,easy,with good reproducibility and suitable for industrial production.关键词
人参/人参皂苷 Rg1/人参皂苷 Re/人参皂苷 Rb1/人参总皂苷/正交试验法Key words
Panax ginseng/ginsenoside Rg1/ginsenoside Re/ginsenoside Rb1/orthogonal design引用本文复制引用
韩宵,朱磊,闫春风,翁慧沥,董海荣..多指标综合加权评分法优选人参醇提工艺[J].中国现代中药,2016,(1):110-113,125,5.
