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基于证候要素的缺血性中风复发风险研究

李新龙 钟非 贺立娟 何丽云 刘霞 韩学医 刘文娜

现代中医临床Issue(1):19-23,5.
现代中医临床Issue(1):19-23,5.DOI:10.3969/j.issn.2095-6606.2016.01.005

基于证候要素的缺血性中风复发风险研究

The risk of ischemic stroke recurrence:an analysis by Cox proportional hazard model based on the TCM pattern factors

李新龙 1钟非 2贺立娟 3何丽云 3刘霞 1韩学医 3刘文娜3

作者信息

  • 1. 中国中医科学院临床基础医学研究所 北京 100700
  • 2. 北京中医药大学东方医院
  • 3. 北京中医药大学东方医院
  • 折叠

摘要

Abstract

Objective To evaluate the influence of various factors,including the TCM pattern factors, on the recurrence of patients with ischemic stroke.Methods A retrospective analysis was underwent for 246 cases of discharged patients with ischemic stroke been treated in Dongfang Hospital of Beijing Univer-sity of Chinese Medicine from July 2004 to November 201 4.Based on their medical records,the patients suffered with ischemic stroke were followed up.A multivariate analysis of the factors was performed by u-sing the Cox proportional hazard regression model.The information of prognosis,including recurrence and death,was collected.Results The recurrence rate of patients with cerebral multiple infarcts was 4.328 times higher than those suffered with cerebral single infarct.1 4 days after admission,risk of recur-rence for the patients with phlegm pattern was 3.463 times higher than that for the patients without phlegm pattern.Furthermore,the risk of recurrence for the patients at the acute stage taking Chinese medicine decoction was only 49.3% of the patients who didn't take.Conclusion Cerebral multiple in-farcts,and phlegm pattern were the independent recurrence factors,and the Chinese medicine decoction was the protective factor at the acute stage.

关键词

缺血性中风/复发/危险因素/证候要素/Cox 比例风险回归模型

Key words

ischemic stroke/recurrence/risk factors/TCM pattern factors/Cox proportional hazard model

分类

医药卫生

引用本文复制引用

李新龙,钟非,贺立娟,何丽云,刘霞,韩学医,刘文娜..基于证候要素的缺血性中风复发风险研究[J].现代中医临床,2016,(1):19-23,5.

基金项目

国家中医药行业专项课题(No.201307001),北京中医药大学重点学科开放课题(No.2013-ZDXKKFKT-38),北京中医药大学自主选题项目 ()

现代中医临床

OACSTPCD

2095-6606

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