长春中医药大学学报Issue(1)：168-170,3.DOI:10.13463/j.cnki.cczyy.2016.01.059
血液灌流联合血液透析对维持性血液透析患者微炎症状态的影响
Blood perfusion in combined with hemodialysis on the micro-inflammation state in patients with maintenance hemodialysis
摘要
Abstract
Objective To explore the effect of blood perfusion in combined with hemodialysis on the micro-in-flammation state in patients with maintenance hemodialysis(MHD). Methods A total of 26 patients with MHD who were admitted in our hospital from July,2014 to July,2015 were included in the study and randomized into the obser-vation group(blood perfusion in combined with hemodialysis group)and the control group(hemodialysis group). The patients in the two groups were given hemodialysis,4. 5 ~ 5 h / time,2 ~ 3 times each week. On this basis,the patients in the observation group were given blood perfusion,2 ~ 2. 5 h / time,once every two week,and given another hemodial-ysis for 2 h after blood perfusion. A3 month treatment was regarded as one course. The levels of CRP,IL-6,TNF-α, SCr,BUN,Ca2 + ,and P3 + before treatment and 3 months after treatment in the two groups were observed and com-pared. Results After 3-month treatment,the levels of CRP,IL-6,and TNF-α in the control group were elevated when compared with before treatment,but the difference was not statistically significant(P ﹥ 0. 05);the levels of CRP,IL-6,and TNF-α in the observation group were significantly reduced when compared with before treatment(P ﹤ 0. 05), and the difference was statistically significant when compared with the control group(P ﹤ 0. 05). After 3-month treat-ment,the levels of SCr,BUN,Ca2 + ,and P3 + in the two groups were significantly reduced(P ﹤ 0. 05),but the compari-son of SCr,and BUN was not statistically significant(P ﹥ 0. 05). The decreased degree of Ca2 + ,and P3 + levels in the observation group was significantly superior to that in the control group(P ﹤ 0. 05). Conclusion Blood perfusion in combined with hemodialysis in the treatment of MHD can produce a favorable synergistic effect,effectively improve the micro-inflammation state,maintain the water-electrolyte balance,improve the residual renal function and clinical symp-toms,and enhance the patients’living qualities.关键词
血液灌流/血流透析/维持性血液透析/微炎症状态Key words
blood perfusion/hemodialysis/maintenance hemodialysis/micro inflammation state分类
医药卫生引用本文复制引用
赵海英..血液灌流联合血液透析对维持性血液透析患者微炎症状态的影响[J].长春中医药大学学报,2016,(1):168-170,3.基金项目
河北省科技研究与发展指导项目（1021057D）。 （）
